RU58841 also named PSK3841 or HMR3841 is a specific androgen receptor antagonist or a so called anti-androgen. This non steroidal topical androgen antagonist was investigated for therapeutic value in androgenetic alopecia and acne. In studies and clinical trials RU58841 has shown to;
Effect of RU58841
Strongly compete against DHT
Increase cellular replication rate in the matrix cells
Increase cellular proliferation of outer root sheeth cells
Increase hair diameter and hair density
Increase the percentage of hair in the anagen phase
Exert no negative effect on body hormone levels
Provide equivalent or better net growth than Finasteride
RU58841 works by binding to the androgen receptor in the hair follicle. Therefore androgens don’t have the chance to bind and start the chain reaction of androgenetic alopecia and begin the so called miniaturization process. It has been demonstrated to interrupt this hair loss message locally so that normal hair growth could continue.
How does RU58841 work?
As an external use of anti-androgen, it and the effect of finasteride principle is not quite same, finasteride direct effects on 5 alpha reductase, containing testosterone into dihydrotestosterone, reduces the DHT levels in the body, and the RU58841 blocking DHT and hair follicle receptors of contact, it does not directly reduce DHT levels, but it reduces the DHT and hair follicle receptors, so as to achieve the purpose of the treatment of male hair loss.
RU58841 powder mixing guide
If you want to mix RU58841 solution, yourself and spare some money and have the extra flexibility that comes with it you will need to mix it. This is actually very simple to do and consists of the following steps:
- Getting legit pure RU58841 powder
- Having a scale that goes by 0.1 or even better 0.01 grams
- Having your vehicle ready where you will mix the powder in. The powder is dissolved in ethanol so make sure the ethanol content is at least 30% and you should have no problems dissolving the RU58841 in the vehicle. For instance it can be mixed in Kirkland minoxidil, neogenic, P&G solution or K&B solution.
- Every 1% of RU represents 10mg/ml. So let’s say you have a Kirkland bottle of 60ml and you want to make a 5% RU solution into this you want to have 50mg/ml x 60 ml = 3 gram. So you add 3 gram to the Kirkland minoxidil and shake it really well. Another example let’s say you want to mix a 3% RU concentration in 10ml of K&B solution you want 30mg/ml x 10ml = 300mg in total.
CERTIFICATE OF ANALYSIS
|Loss on dryin||≤0.1%||0.05%|
|CONCLUSION||The result conform with standard|