IGF-1 LR3 available stock in USA

Available Stock

IGF-1 LR3 500vails available stock in USA

IGF-1 LR3 500vails available stock in UK

Unit Size: 0.1mg/vail, 1mg/vial
Unit Quantity: 10 vials

Physical and chemical properties
Molecular Weight 9117.5
Physical Appearance White lyophilised solid
Purity >98%
Form & Formulations Sterile filtered white lyophilized (freeze-dried)
Solubility Aqueous soluble
Storage Lyophilized peptides although stable at room temperature for 3 months, should be stored desiccated below -18°C. Upon reconstitution of the peptide it should be stored at 4°C between 2-21 days and for future use below -18°C.
Analytical Data
HPLC shows min 98% Purity
Mass Spectrum Consistent with structure
Research use
Caution Research use only / Not for human or veterinary use

 

The polypeptide Long R3 Insulin-like Growth Factor-I (IGF1 LR3) is an 83 amino acid analog of IGF-I actually comprising the complete IGF-1 sequence but with the substitution of an Arginine (Arg) for the Glutamic Acid (Glu) at position 3, as well as a 13 amino acid extension peptide. This sequence change causes IGF-1 LR3 to avoid binding to proteins and allow it to have a much longer half life, around 20-30 hours. This analog of IGF-1 has been produced with the purpose of increasing the biological activity of the IGF peptide.” IGF stands for insulin-like growth factor. Among the effects the most positive are increased amino acid transport to cells, increased glucose transport, increased protein synthesis, and decreased protein degradation. When IGF is active it behaves differently in different types of tissues. In muscle cells proteins and associated cell components are stimulated. Protein synthesis is increased along with amino acid absorption. As a source of energy, IGF-1 LR3 mobilizes fat for use as energy in adipose tissue. In lean tissue, IGF-1 LR3 prevents insulin from transporting glucose across cell membranes. As a result the cells have to switch to burning off fat as a source of energy.

 

The Half-Life of IGF-1 LR3 and its Effects of IGF-1


It has a considerably longer half-life than other form, nearly 20-30 hours. When IGF-1 LR3 is active, has multiple effects on tissues in muscle cells. It plays a essential role in muscle renewal. IGF-1 LR3 encourages both increase as well distinction of stem cells. IGF-1 LR3 increases satellite cell activity, muscle DNA, muscle protein content, muscle weight and muscle cross sectional area. The importance of IGF-1 LR3 lies in the fact that all of its obvious effects work to induce muscle growth. These effects are enhanced when combined with weight training.

Research Use of IGF-1 LR3

– enlarged amino acid transporting cells
– increased protein production
– reduced protein degradation
– amplified glucose transporting
– augmented RNA combination

This product is intended as a research chemical only, the product is used only for production or research.